145 research outputs found

    "You have to get wet to learn how to swim" applied to bridging the gap between research into personnel scheduling and its implementation in practice

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    Personnel scheduling problems have attracted research interests for several decades. They have been considerably changed over time, accommodating a variety of constraints related to legal and organisation requirements, part-time staff, flexible hours of staff, staff preferences, etc. This led to a myriad of approaches developed for solving personnel scheduling problems including optimisation, meta-heuristics, artificial intelligence, decision-support, and also hybrids of these approaches. However, this still does not imply that this research has a large impact on practice and that state-of-the art models and algorithms are widely in use in organisations. One can find a reasonably large number of software packages that aim to assist in personnel scheduling. A classification of this software based on its purpose will be proposed, accompanied with a discussion about the level of support that this software offers to schedulers. A general conclusion is that the available software, with some exceptions, does not benefit from the wealth of developed models and methods. The remaining of the paper will provide insights into some characteristics of real-world scheduling problems that, in the author’s opinion, have not been given a due attention in the personnel scheduling research community yet and which could contribute to the enhancement of the implementation of research results in practice. Concluding remarks are that in order to bridge the gap that still exists between research into personnel scheduling and practice, we need to engage more with schedulers in practice and also with software developers; one may say we need to get wet if we want to learn how to swim

    Genome-wide inference of regulatory networks in Streptomyces coelicolor

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    Background: The onset of antibiotics production in Streptomyces species is co-ordinated with differentiation events. An understanding of the genetic circuits that regulate these coupled biological phenomena is essential to discover and engineer the pharmacologically important natural products made by these species. The availability of genomic tools and access to a large warehouse of transcriptome data for the model organism, Streptomyces coelicolor, provides incentive to decipher the intricacies of the regulatory cascades and develop biologically meaningful hypotheses. Results: In this study, more than 500 samples of genome-wide temporal transcriptome data, comprising wild-type and more than 25 regulatory gene mutants of Streptomyces coelicolor probed across multiple stress and medium conditions, were investigated. Information based on transcript and functional similarity was used to update a previously-predicted whole-genome operon map and further applied to predict transcriptional networks constituting modules enriched in diverse functions such as secondary metabolism, and sigma factor. The predicted network displays a scale-free architecture with a small-world property observed in many biological networks. The networks were further investigated to identify functionally-relevant modules that exhibit functional coherence and a consensus motif in the promoter elements indicative of DNA-binding elements. Conclusions: Despite the enormous experimental as well as computational challenges, a systems approach for integrating diverse genome-scale datasets to elucidate complex regulatory networks is beginning to emerge. We present an integrated analysis of transcriptome data and genomic features to refine a whole-genome operon map and to construct regulatory networks at the cistron level in Streptomyces coelicolor. The functionally-relevant modules identified in this study pose as potential targets for further studies and verification.

    Effect of different microwave-based treatments on multi-walled carbon nanotubes

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    Three new methods for the functionalization of multi-walled carbon nanotubes (MWCNTs) are reported using microwave (MW) energy and water as a mild chemical agent. In the first method we reported the effect of MW irradiation on a dispersion of MWCNTs in deionized water, in the second method we studied the exposing of MWCNT to microwave irradiation in the presence of steam, and in the third method we used microwave oven-generated plasma for the functionalization of MWCNTs. We also performed thermal oxidation and acid treatment as two conventional methods for oxidative functionalization of carbon nanotubes, to compare their effect with our results. Transmission electron microscopy (TEM) and Raman spectroscopy results showed that although these microwave methods introduced some defects to the carbon nanotubes, the damage was less severe than conventional treatments. X-ray photoelectron spectroscopy (XPS) measurements confirmed that the functionalization of carbon nanotubes by these methods favored hydroxyl groups, which are useful when further functionalization is required.Pejman Hojati-Talemi, Raoul Cervini, George P. Simo

    Deposition Rate, Mineralogy and Size Distribution Pattern of Dust Particles Collected Around the Houralazim Marshland, Khuzestan Province

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    Introduction: Recently, air pollution due to the occurrence of dust storms is one of the worst environmental problems in Western and Southwestern Iran, especially the Khuzestan Province (12, 13). According to the reports of the Meteorological Organization of Iran the average number of dusty days in the cities of Ahvaz and Abadan in the Khuzestan Province reaches 68 and 76 days each year, respectively (6). Previous studies have shown that the yearly damage costs of wind erosion and occurrence of dust storms in the Khuzestan Province reach about 30 Billion Rials (5). However, very few studies have been conducted on the characterization of dust particles and also the identification of their origins in Iran, especially the Khuzestan Province. Hojati et al. (10) reported that dust deposition rate, mean particle diameter, and concentration of soluble ions in samples taken from Isfahan and Chaharmahal and Bakhtiari Province decrease with altitude, with a significantly lower gradient in periods with dust storms. They reported three factors that control the rate and characteristics of dust deposited across the study transect: 1) climatic conditions at the deposition sites, 2) distance from the dust source, and 3) differences between local and transboundary sources of dust.Therefore, this study was conducted to investigate the effects of dust storms on deposition rate, mineralogy and size distribution patterns of dust particles from twelve localities around the Houralazim lagoon. Materials and Methods: Dust samples were collected monthly during a 6 month experiment from August 2011 to February 2012. In order to differentiate between the contribution of dust production by local soils and other sources, surface soils were also sampled from the vicinity of the dust sampling sites. The collection trays were made of a glass surface (100 × 100 cm) covered with a 2 mm-sized PVC mesh on the top to form a rough area for trapping the saltating particles (Fig. 2). Dust samples were collected by scraping materials adhered to the glass trays using a spatula. All the trays were wet cleaned before the next collection. The collected dust and soil samples were examined for their grain size distribution using a Malvern Hydro 2000g laser particle size analyzer, as well as their mineral compositions by a Philips PW1840 X-ray diffractometer and a LEO 906 E transmission electron microscope (TEM). Results and Discussion: The results showed that wind speed and direction patterns during the periods with dust storms and those without dust storms were different. Accordingly, in periods with dust storms (3, 5 and 6) the contribution of winds with speeds greater than 11.1 m/sec, especially from the Northwest direction, increased when compared with those from the periods without dust storms (1, 2 and 4). Besides, the direction of prevailing winds in periods without dust storms were mainly from the West and the Northwest. However, in periods with dust storms East-directed winds were also observed (Fig. 3). These show that the source areas of dust particles in these periods are probably different. The results also illustrated that the average amount of deposited particles in the periods with dust storms (12.5 g m-2 month-1) was considerably more than that of the periods without dust storms (7.5 g m-2 month-1) (Figs. 4 and 5). The difference in dust deposition rate between periods having dust storms and those without dust storms seems to be due to dust input from a source outside the study area. Particle size distribution analysis showed that dust particles collected from the study area in both periods (with and without dust storms) are mainly silt-sized particles. This fraction contributes to 60 to 76 % of the particles collected from periods without dust storms and 66 to 82 % of particles affected by dust storms (Table 2). The results also imply that in both periods (with and without dust storms), dust particles collected from the study area had a bimodal distribution pattern which suggests mixing of settled particles from different sources and/or deposition processes (Fig. 6). Mineralogical composition of dust particles were collected from both periods (with and without dust storms) and those from the soils contained quartz, calcite, feldspar, halite, dolomite and palygorskite (Figs. 7 and 8). Moreover, the TEM images of dust particles collected in periods with dust storms showed higher amounts of palygorskite than in periods without dust storms (Fig. 9). Conclusion: The similarity in the physical properties of local soils and deposited particles of the periods with and without dust storms implies that the contribution of local soils and sediments in producing dust particles is high. However, it seems that in periods with dust storms the contribution of a transboundary origin such as Iraqi arid lands in producing dust particles increases

    Retracted: Research self-efficacy of students in Jahrom University of medical sciences: a cross-sectional descriptive study in 2017

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    This article was withdrawn and retracted by the Journal of Fundamental and Applied Sciences and has been removed from AJOL at the request of the journal Editor in Chief and the organisers of the conference at which the articles were presented (www.iccmit.net). Please address any queries to [email protected]
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